化痰活血中药在老年肺部感染患者中的治疗效果研究

Study on the therapeutic effect of traditional Chinese medicine for eliminating phlegm and activating blood circulation in aged patients with pulmonary infection

目的:为研究中医药在肺部感染疾病治疗中的应用优势,对老年肺部感染患者采取化痰活血中药治疗,并研究其治疗效果。方法:选取2017年1月-2019年1月到我院进行治疗的60例老年肺部感染患者,中医辨证为血瘀痰阻证。采取随机数字表法,将患者随机分为两组。对照组30例患者给予常规治疗,根据药敏试验结果给予抗生素,同时给予营养支持、维持水电解质平衡等;在此基础上,观察组30例患者使用自拟化痰活血方治疗,基本药方组成包括薏苡仁、瓜蒌皮、法半夏、陈皮、地龙、僵蚕、丹参、虎杖、杏仁、桃仁、浙贝母、莪术、桔梗等,并根据患者具体症状采取加减疗法。结果:观察组患者总有效率为96.67%,对照组患者总有效率为80%,差异明显(χ2=4.04,P<0.05);治疗前,观察组与对照组患者的中医症状积分分别为(35.57±8.07)分、(36.20±7.64)分,无明显差异(t=-0.311,P>0.05);治疗后,观察组患者的中医症状积分为(14.56±6.58)分,对照组为(22.19±7.34)分,差异明显(t=-4.239,P<0.05);治疗后,观察组患者的WBC计数、PCT、CRP水平均明显低于对照组(P<0.05)。结论:对老年肺部感染患者采取化痰活血中药辅助治疗能够提升整体疗效,减轻患者临床症状,促进炎症控制,具有推广价值。

Objective: In order to study the application advantage of traditional Chinese medicine in the treatment of pulmonary infection, the aged patients with pulmonary infection were treated with traditional Chinese medicine to reduce phlegm and promote blood circulation, and the therapeutic effect was studied. Methods: From January 2017 to January 2019, 60 elderly patients with pulmonary infection who were admitted to our hospital for treatment were selected. Patients were randomly divided into two groups by random number table method. In the control group, 30 patients were given routine treatment, antibiotics were given according to the results of drug sensitivity test, and nutritional support and water and electrolyte balance were also given. On this basis, 30 patients in the observation group were treated with self-made phlegm-resolving and blood-activating prescription. The basic prescription consisted of coix seed, snakegourd peel, pinellia tuber, orange peel, earthworm, silkworm batterii, salvia miltiorrhiza, polygonum cuspidatum, almond, peach kernel, fritillaria thunbergii, zedoary turmeric and radix platycodonis. Results: The total effective rate was 96.67% in the observation group and 80% in the control group, which was with a significant difference (χ2 = 4.04, P < 0.05). Before treatment, the TCM symptom scores of the patients in the observation group and the control group were (35.57±8.07) and (36.20±7.64) respectively, which was with no significant difference (t =-0.311, P > 0.05). After treatment, the TCM symptom score of the patients in the observation group was (14.56±6.58), and that of the control group was (22.19±7.34), which was with significant difference (t =-4.239, P < 0.05). After treatment, WBC count, PCT and CRP levels in the observation group were significantly lower than those in the control group (P < 0.05). Conclusion: The adjuvant treatment of traditional Chinese medicine for resolving phlegm and activating blood circulation for elderly patients with pulmonary infection can improve the overall efficacy, reduce the clinical symptoms of patients, and promote the control of inflammation, which has the promotion value.