加味黄连汤结合针灸治疗中老年女性失眠患者临床疗效观察

Clinical observation of Modified Huanglian Decoction combined with acupuncture and moxibustion in the treatment of middle-aged and elderly women with insomnia

目的:探讨加味黄连汤结合针灸治疗中老年女性失眠患者临床疗效的影响。方法:选取我院门诊诊断并治疗的中老年女性失眠患者50例,患者或家属签字同意,随机分为对照组与治疗组,每组25例。对照组患者予以阿普唑仑片口服0.8mg晚睡前口服,治疗组在对照组基础上予以加味黄连汤结合针灸治疗。治疗结束后比较两组患者临床有效率、中医病症评分、匹兹堡睡眠质量指数评分(PSQI),同时对比两组患者不良反应及复发情况。结果:治疗组临床总有效率88.00%高于对照组治疗总有效率64.00%,具有统计学意义(P<0.05);与治疗前比较,两组患者中医病症评分、PSQI评分较低(P<0.05);与对照组比较,治疗组患者中医病症评分、PSQI评分较低(P<0.05),随访失眠复发较低(P<0.05)。结论:加味黄连汤结合针灸治疗对中老年女性性失眠患者具有较好的临床疗效,有效提高睡眠时间及质量,不良反应少。

Objective: To explore the clinical effect of Modified Huanglian Decoction (加味黄连汤) combined with acupuncture and moxibustion in the treatment of middle-aged and elderly women with insomnia. Methods: 50 cases of middle-aged and elderly female insomnia patients diagnosed and treated in our outpatient department were selected, and the patients or their families signed their consent. They were randomly divided into the control group and the treatment group, with 25 cases in each group. Patients in the control group were given alprazolam tablets by oral administration of 0.8mg at night before going to bed, and patients in the treatment group were given Modified Huanglian Decoction combined with acupuncture treatment on the basis of the treatment of the control group. After treatment, the clinical efficiency, TCM symptom score and Pittsburgh sleep quality index score (PSQI) were compared between the two groups, and adverse reactions and recurrence were compared between the two groups. Results: The clinical effective rate of the treatment group was 88.00%, which was higher than that of the control group (64.00%), which was with statistical significance (P < 0.05). Compared with that before treatment, the scores of TCM symptoms and PSQI in the two groups were lower (P < 0.05). Compared with the control group, patients in the treatment group had lower TCM symptoms score and PSQI score (P < 0.05), and follow-up insomnia recurrence was lower (P < 0.05). Conclusion: Modified Huanglian Decoction combined with acupuncture and moxibustion has a good clinical effect in the treatment of middle-aged and elderly women with insomnia, it can effectively improve the sleep time and quality, and it is with less adverse reactions.