柏子仁化学成分与药理活性研究进展

Advances in chemical constituents and pharmacological activities of arboruitae seed

柏子仁(arboruitae seed),为柏科植物侧柏Platycladus orientalis(L.) Franco的干燥成熟种仁.在化学成分方面,柏子仁含有脂类、氨基酸、皂苷、萜类和多糖等有效成分,具有镇静安神、抗抑郁、减少小鼠自主活动次数、改善阿尔茨海默病、加强肠推进、治疗不孕症等作用.本文对柏子仁的化学成分、药理活性和临床应用等相关研究进行综述,以指导该药物的开发利用,并为临床合理应用提供可靠的参考.

Arboruitae seed is the dry mature seed of Platycladus orientalis (L.) Franco. In terms of chemical constituents, arboruitae seed contains lipids, amino acids, saponins, terpenoids and polysaccharides. It has the functions of calming and tranquilizing nerves, anti-depression, reducing the number of spontaneous activities in mice, improving Alzheimer's disease, strengthening intestinal propulsion and treating infertility. In this paper, the chemical constituents, pharmacological activities and clinical application of arboruitae seed were reviewed in order to guide the development and utilization of the drug and provide reliable reference for rational clinical application.