4Yang S,Xu SX’Xiao FL’et al. Prevalence and familial riskof ephelides in Han Chinese adolescents [ J ]. Arch Der-matol Res,2008,300(2) :87 -90.
5Zhang XJ, He PP, Liang YH, et al. A gene for frecklesmaps to chromosome 4q32-q34[J]. J Invest Dermatol,2004,122(2) :286-290.
6Eriksson N,/V\acpherson JM,Tung J丫,et al. Web-based,participant-driven studies yield novel genetic associa-tions for common traits [ J ]. PLoS Genet, 2010,6(6):el000993.
7Jacobs LC’Wollstein A,Lao 0,et al. Comprehensive can-didate gene study highlights UGT1A and BNC2 as newgenes determining continuous skin color variation in Eu-ropeans[J]. Hum Genet,2013,132(2) :147 - 158.
8Sulem P,Gudbjartsson DF,Stacey SN’et al. Two newly i-dentified genetic determinants of pigmentation in Euro-peans[J]. Nat Genet,2008,40(7) :835 -837.
9Sulem P,Gudb|artsson DF,Stacey SN,et al. Genetic de-terminants of hair,eye and skin pigmentation in Europe-ans[J]. Nat Genet,2007,39( 12) : 1443 - 1452.
10Motokawa T,Kato T,Hashimoto Y,et al. Polymorphismpatterns in the promoter region of the MCI R gene areassociated with development of freckles and solar len-tigines [ J ]. J Invest Dermatol,2008, 128 (6) : 1588 -1591.
