腹腔镜治疗肥胖症阑尾炎对患者术后生活质量及炎性因子影响研究

Effect of laparoscopic treatment on quality of life and postoperative inflammatory factors in patients with obese appendicitis

目的:探讨腹腔镜治疗对肥胖阑尾炎患者术后生活质量及炎性因子水平的影响。方法:选取近2年所收治的100例肥胖阑尾炎患者,根据不同手术方式,将其分为腹腔镜手术组与传统手术组,每组患者50例,腹腔镜手术组采取腹腔镜手术,传统手术组采取传统开腹手术治疗,对比两种手术方式对肥胖阑尾炎患者生活质量及术后炎性因子水平影响。结果:腹腔镜手术组患者的各项临床指标均明显优于传统手术组,手术时间、下床时间、肛门排气时间、进食水时间、住院时间较传统手术组短,术中出血量较传统手术组少,差异具有统计学意义(P<0.05);两组患者手术前生活质量评分对比差异无统计学意义(P>0.05),两组患者术后生活质量均有所提高,且腹腔镜手术组患者的生活质量评分明显高于传统手术组(P<0.05);两组患者手术前肿瘤坏死因子-α(TNF-a)、血清C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)对比差异无统计学意义(P>0.05),手术后,腹腔镜手术组患者TNF-a、CRP、IL-6、IL-8明显低于传统手术组,差异显著(P<0.05)。结论:腹腔镜手术治疗肥胖阑尾炎患者效果更优,可减少创伤,降低炎性反应,有利于患者快速康复,提高患者的生活质量,具有明显优势。

Objective:To investigate the effect of laparoscopy on the quality of life and postoperative inflammatory factors in patients with obese appendicitis.Methods:100 patients with obese appendicitis admitted to our hospital in the past 2 years were divided into laparoscopic surgery group and traditional operation group according to different surgical methods.50 patients in each group were treated with laparoscopic surgery in laparoscopic surgery group.The traditional operation group was treated with traditional open surgery,and the effects of the two surgical methods on the quality of life and postoperative inflammatory factors in patients with obese appendicitis were compared.Results:The clinical indexes of the patients in the laparoscopic surgery group were significantly better than those in the traditional operation group.The operation time,bed-out time,anal exhaust time,feeding time,and hospitalization time were shorter than those of the traditional operation group.There were few differences in the operation group(P<0.05).There was no significant difference in the quality of life scores between the two groups(P>0.05).The postoperative quality of life was improved in both groups,and laparoscopic surgery was performed.The quality of life scores of the patients in the group were significantly higher than those in the traditional operation group(P<0.05).There was no significant difference in the preoperative TNF-a,CRP,IL-6 and IL-8 between the two groups(P>0.05).The levels of TNF-a,CRP,IL-6 and IL-8 in the laparoscopic surgery group were significantly lower than those in the conventional surgery group(P<0.05).Conclusion:Laparoscopic surgery for patients with obese appendicitis is more effective,can reduce trauma,reduce inflammatory reaction,is conducive to rapid rehabilitation of patients,improve patients'quality of life,has obvious advantages,and is promoted clinically.