支气管袖状切除术与全肺切除术在老年非小细胞肺癌中的应用比较

Comparison of efficacy of bronchial sleeve resection and pneumonectomy in treatment of elderly patients with non-small cell lung cancer

目的对支气管袖状切除术与全肺切除术在老年非小细胞肺癌患者治疗中的应用效果进行比较。方法选取2016年4月-2017年4月安阳市肿瘤医院收治的非小细胞肺癌患者90例,根据其治疗的方法分为实验组和对照组各45例,对照组给予全肺切除术,实验组给予支气管袖状切除术。结果实验组手术时间为(118.45±21.34)min,对照组手术时间为(110.34±22.44)min,组间对比差异无统计学意义(P>0.05),实验组术中出血量为(254.38±32.46)ml,住院时间为(11.68±3.12)d,对照组术中出血量为(423.87±54.54)min,住院时间为(18.75±5.45)d,组间对比差异有统计学意义(P<0.05);两组患者术前各项指标,如第1s用力呼气量、用力肺活量、自测呼气峰值流速均无显著差异,P>0.05,但是术后实验组各项肺功能指标情况均优于对照组,组间对比差异有统计学意义P<0.05;且实验组总并发症发生率为8.89%,对照组为20.00%,组间对比差异有统计学意义P<0.05。结论临床上对于治疗非小细胞肺癌采取支气管袖状切除术治疗效果确切,值得推广。

Objective To compare the efficacy of bronchial sleeve resection and pneumonectomy in the treatment of elderly patients with non-small cell lung cancer. Methods A total of 90 patients with non-small cell lung cancer admitted to Anyang Cancer Hospital from April 2016 to April 2017 were selected. According to their treatment methods, the patients were divided into the experimental group and the control group, 45 cases each. The control group received pneumonectomy, and the experimental group received bronchosleeve resection.Results The operative time of experiment group was(118.45±21.34) min, the control operation time of control group(110.34±22.44) min, comparing differences between groups have no statistical significance(P>0.05), bleeding amount of experimental group is(254.38±32.46)ml, length of hospital stay(11.68±3.12) d, bleeding amount of control group(423.87±54.54) min, length of hospital stay(18.75±5.45) d, comparing differences between groups was statistically significant(P<0.05);There was no significant difference between the two groups in preoperative indicators, such as forced expiratory volume in the first 1 s, forced vital capacity, and self-measured peak expiratory velocity(P>0.05), but the pulmonary function indicators in the experimental group were better than those of the control group after surgery, with statistically significant difference(P<0.05). The total complication rate of the experimental group was 8.89%, significantly higher than that of the control group(20.00%), and the difference was statistically significant(P<0.05). Conclusion Bronchial sleeve resection is an effective treatment for non-small cell lung cancer.