肺静脉血流频谱对高血压心脏病患者左室舒张功能的研究

The assessment of left ventricular diastolic function by determining pulmonary venous flow in patients with hypertension heart disease

目的 探讨超声心动图检测肺静脉血流频谱的变化无创评价高血压心脏病患者左室舒张功能的价值。方法 选择无心脏病史并经体检和辅助检查正常者30例为对照组,高血压病Ⅱ期患者30例为研究对象。使用频谱多普勒记录肺静脉和二尖瓣口血流频谱及心功能的有关参数,观察各组病人肺静脉血流速度的变化和左室舒张功能的关系。结果 高血压组PVF频谱参数较对照组有显著差异(P<0.05),表现为PVd峰下降,PVs峰上升,PVs/PVd>1,PVa峰升高。结论 肺静脉血流相对较独立,受年龄的影响较小,是较可靠的指标。PVF频谱与MVF频谱结合可较全面评价左室的舒张功能,对于判断左室舒张功能的障碍程度、治疗的效果和病程的转归均具有重要意义。

Objectives To investigate the value of noninvasive assessment of left ventricular dias-tolic function in patients with hypertension heart disease by pulmonary venous flow (PVF). Methods Peak velocity of pulmonary venous flow, mitral valve flow and the parameter of cardiac function were measured by pulse Doppler in 30 patients with second stage of hypertension, and 30 subjects were in control group the relationsinp between the change of pulmonary ve- nous flow and left ventricular function were analyzed. Results Paired t-test showed significant difference between two group of PVF (P < 0.05) : PVd reduced and PVs increased, PVs/PVd , 1, PVa increased in hypertension group. Conclusions Pulmonary venous flow is relatively independent, less influence by age and a reliable index, it has importent significance to decide left ventricular function obstruction, therapeutic effect and prognosis of disease.