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细胞心肌成形术-心肌再生的突破 被引量：2

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摘要 心肌细胞是人体心脏最基本的结构和功能单位.不论是什么类型的心脏疾病,它所引起的心脏功能的变化,从本质上说,都是心肌细胞的变性坏死造成的.在成熟个体中,心肌属于最终分化细胞,一旦损伤只能由疤痕组织代替.如何促使心肌细胞再生一直是心血管领域的一个重要的研究课题.
作者 盛小刚
机构地区 广东省心血管病研究所心内科
出处 《岭南心血管病杂志》 2002年第5期363-366,共4页 South China Journal of Cardiovascular Diseases
关键词 细胞心肌成形术 心肌再生 心肌细胞移植
分类号 R654.2 [医药卫生—外科学]
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参考文献30

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同被引文献12

  • 1张文,田杰,江德勤,张蕾,朱静,陈沅.骨髓间充质干细胞体外分化为心肌样细胞相关调控基因的时序表达[J].中华心血管病杂志,2004,32(11):1004-1008. 被引量：25
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  • 5[5]Hakuno D,Fukuda K,Makino S,et al.Bone marrow-derived regenerated cardiomyocytes (CMG cells) express functional adrenergic and muscarinic receptors[J].Circulation,2002,105 (3):380-386.
  • 6Makino S, Fukuda K, Miyoshi S, et al. Cardiomyocytes can be generated from marrow stromal cells in vitro[J]. J Clin Invest,1999,103(5) : 697- 705
  • 7Tomita S,Mickle DA,Weisel RD,et al. Improved heart function with ntyogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplatation [ J]. J Thorae Cardiovasc Surg,2002,123(6):1 132-1 140
  • 8Shake JG, Gruber PJ, Baumgarmer WA, et al. Mesenehymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects[J]. Ann Thorae Surg,2002,73(6):1 919-1 925
  • 9Wang J, Shum- Tim D, Galipeau J, et al. Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages[J]. J Thorac cardiovasc Surg, 2000,120:99-1 006
  • 10Tomita K, Li RK, Weisel RD, et al. Autologous transplantation of bone marrow cells improves damaged heartfunction[J]. Circulation,1999,100:11- 247

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岭南心血管病杂志
2002年 第5期

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