摘要
本研究首次证明,绿茶多酚类的主要成分没食子酰表没食子儿茶素(EGCG)具有很强的抑制促癌物TPA诱导的皮肤炎性水肿和增生反应,以及抑制TPA促进经甲基胆蒽启动的BALB/3T3细胞的转化作用。本实验结果表明,EGCG可能是绿茶多酚提取物中抑制TPA促癌作用的重要成分。
This experiment demonstrated that epigallocatechin gallate(EGCG), the main component in green tea poly-phenols, showed a strong inhibitory effect on TPA-induced edema and hyperplasia in mouse skin, and TPA-induced promotion effect in BALB/3T3 cells initiated by 3-methylcholanthrene.
These experimental results indicate that EGCG is probably the main component in green tea polyphenols which inhibit TPA-induced promotion.
出处
《癌变．畸变．突变》
CAS
CSCD
1992年第1期1-4,共4页
Carcinogenesis,Teratogenesis & Mutagenesis
