支气管动脉灌注化疗治疗肺癌214例报告

DSA DIAGNOSES ANG BAI TREATMENT OF LUNG CARCINOMA

本文报告了214例经DSA诊断和BAI治疗的不能手术肺癌病例。全部病例采用Sel-dinger氏法直接穿刺股动脉插入F_7号导管,做选择性支气管动脉灌注化疗药物。化疗药物选用丝裂霉素(每次8—14mg)和顺铂(每次40—60mg)。DSA诊断正确率99.1％。BAI治疗近期效果满意。有效率为92％,完全缓解18例(8.3％<),部分缓解139例(65％),稳定40例(18.7％),病变发展17例(8％)。并为9例(4.2％)Ⅲ期肺癌患者争取了手术切除癌肿的机会。故DSA对肺癌的诊断;BAI对肺癌的治疗是很有价值的。

This paper presents 214 cases of inoperable lung carcinoma diagno-sed by Digital Substractive Angiography (DSA)and treated with Bronchioarterial Infusion (BAD. The DSA was conducted with seldinger 's method by femoral artery puncture; and the BAI was performed by injecting chemical theraptec agents into the bronchial artery selectively. The mitomycin C (8 - 14mg per injection) and cisplatin(40 - 60mg per injection) were used for BAI treatment. The accuracy of DSA diagnosis was 99.1%. The short-term outcome of BAI treatment was as follows: complete remission in cases (8.3% ),part-ial remission in 139 cases (65%), stable disease in 40 cases (18.7%), pregress of disease in 17 cases (8%). In addition, after BAI nine cases(4.2%) obtained the opportunity of op-operative treatment. Therefore, DSA and BAI are worth for the diagnoses and treatment for the lung carcinoma.