摘要
牛磺酸(Taurine,Tau.2-氨基乙磺酸)为体内一种β-氨基酸,属于非蛋白质氨基酸。主要分布在兴奋性较高的组织如神经系统、肌肉组织、视网膜及血小板中。近年来研究认为牛磺酸不仅参与合成胆汁酸、调节渗透压、阻断神经冲动的功能,还有抗氧化及维持膜稳定性等方面作用。
Taurine is a ubiguitious amino acid in the animal kingdom. Tt is found widely throughout the body and in particularly high concentrations in heart. Availbale evidence implies that taurine may serve a homestatic founction in heart by stablizing membrane through the regulation of cell membrane permeability to ions.
Taurine influance K^+, Cl^- and Ca^(2+) translocation in heart. Recently, taurine was found that it may inhabit the membrane protein phsophloration involved Ca CaM system.
Taurine is higher than noral ammounts in states of cardiovascular pathology; i.e. congestive heart failure and hypertension in men. Taurine can also protect the heart from drug-induced acute damage.
关键词
心脏病
牛磺酸
氨基酸
Taurine
Heart
Cell membrane
Ca^(2+)
