泌尿系统金黄色葡萄球菌感染125例分析

The staphylococcus infection of the urinary system

目的:探讨泌尿系统金黄色葡萄球菌感染的现状、耐药性及其治疗。方法:对125株感染泌尿系的金黄色葡萄球菌进行回顾性分析。结果:本组中耐甲氧西林金黄色葡萄球菌(MRSA)89株(71.2%),甲氧西林敏感金黄色葡萄球菌(MSSA)36株(28.8%)。医院内感染77株(61.6%),71株为MRSA(92.2%)。MRSA对青霉素类耐药率很高,对头孢类、氨基糖甙类和新型喹诺酮类抗生素均有程度不同的耐药,而对万古霉素100%敏感。结论:金黄色葡萄球菌是泌尿系感染重要的致病菌,其中MRSA占很大比重。MRSA的治疗应在药敏试验指导下用药,对于全身重度感染,万古霉素为首选。

Objective: To study the current situation and drug resistance, treatment of urinary infection caused by staphylococcus aureus. Methods: 125 strains of staphylococcus aureus causing urinary infection were reviewed. Results: 89 (71.2%) strains were MRSA, 36 (28.8%) strains were MSSA. 77(61.6%) of the total cases occurred in hospital. The rate of staphylococcus resistant to penicillin was very high, having different resistance to cephalosponis and gentamycin, ciprofloxacin, but all were sensitive to vancomycin. Conclusions: Staphylooccus aureus is very important cause for urinary infection, most of which are MRSA. Sensitive antibiotics should be selected with the guidance of drug sensitivity test in the treatment of MRSA infection . Vancomycin is the drug of choice.