电解损毁室旁核对免疫机能的影响

Effect of Electrolytic Lesion of Paraventricular Nucleus on Immune Functions

本文通过电解损毁的方法观察了室旁核对免疫机能的影响。结果表明:电解损毁大鼠室旁核,大鼠的皮肤迟发性超敏反应,脾抗体形成细胞溶血反应,腹腔巨噬细胞吞噬活性及脾细胞对丝裂原刀豆素A(ConA)的反应性均增强。结果提示室旁核在神经免疫调节中起重要作用。

By means of electrolytic lesion, the influence of Paraventricular Nucleus (PVN) on immune function was observed in rats. The results showed that after PVN was damaged, the delayed skin hypersenstivity, spleen plaque—forming cells reaction, the phagoeytosis of abdominal macrophages and the response of spleen cells to mitogen Con A stimulation all increased. The results indicate that PVN plays an important role in neuro—immuno—modulation.