摘要
Ｐｈａｒｍａｃｏｋｉｎｅｔｉｃｓｌｏｃａｌｍｏｄｅｌａｎｄｉｔｓａｐｐｌｉｃａｔｉｏｎｉｎ ｎｕｃｌｅａｒｍｅｄｉｃｉｎｅＣａｏＧｕｏ－Ｘｉａｎ（曹国宪）；ＬｉＷｅｉ－Ｙｉ（李卫一）ａｎｄＹｕＨｕｉ－Ｘｉｎ（俞惠新）（ＪｉａｎｇｓｕＩｎｓｔｉｔｕｔｅ...
The Pharmacokinetics local model for studying kinetic action of pharmaceuticals in the specific part of the body is established on the basis of the compartment model.A series-of formulae is deduced,and with them the pharmacokinetic equation and several important parameters can be obtained. The local model successfully expanded the area ofpharmacokinetics from the compartment model, which is mainly dealing with kinetic action of pharmaceuticals in blood,to the local model,which can study kinetic action of pharmaceuticals in any organ j tissue or fluid.
关键词
放射医学
药物动力学
数学模型
计算机程序
Pharmacokinetics,Mathematical model,Local model,Computer program.
