摘要
Columbia University microbeam was constructed in 1993 and finished by the end of 1995. It is well established and used routinely to irradiate cells in a highly localized spatial region with a defined number of α-particles. By using this probe, it is possible to study a number of radiobiological questions in ways that cannot be simulated by using conventional broad-field exposures. This report describes the development and current capabilities of the Columbia University microbeam, as well as the preliminary researches undertaken.
Columbia University microbeam was constructed in 1993 and finished by the end of 1995. It is well established and used routinely to irradiate cells in a highly localized spatial region with a defined number of α-particles. By using this probe, it is possible to study a number of radiobiological questions in ways that cannot be simulated by using conventional broad-field exposures. This report describes the development and current capabilities of the Columbia University microbeam, as well as the preliminary researches undertaken.
关键词
放射生物学
微射束
靶细胞
实验系统
Single particle, Microbeam, Irradiation, Radiobiological effects
