Sustained mutagenic effect in bone marrow cells induced by signal nuclide ^(134)Cs retention in skeleton

Ｓｕｓｔａｉｎｅｄｍｕｔａｇｅｎｉｃｅｆｅｃｔｉｎｂｏｎｅｍａｒｒｏｗｃｅｌｓｉｎｄｕｃｅｄｂｙｓｉｇｎａｌｎｕｃｌｉｄｅ１３４ＣｓｒｅｔｅｎｔｉｏｎｉｎｓｋｅｌｅｔｏｎＺｈｕＳｈｏｕＰｅｎｇ，ＸｉａＦｅｎａｎｄＹａｎｇＷｅｉＤｏｎｇ（Ｓｕｚｈ...

The skeleton transference and the retention dynamics of i.v. 134 Cs are investigated. Results indicate that the retention percentage of 134 Cs in skeleton could be characterized by R(t) =0.0029 exp (-0.121 t )with T 1/2 = 5.73 d; the chromosome aberration percentage of somatic bone marrow cells increases obviously, the relationship between injected dose ( X in kBq/g) and the chromosome aberration percentage can be expressed as Y =0.0561X 0.427 .It should be noted that sustained elevation of chromosomal aberration rates induced by 134 Cs can be upto the 47 th d.