摘要
对31例Ⅱa型、31例Ⅱb型、153例Ⅳ型高脂血症患者及100例年龄相近的正常人血清apoAl、B及其血脂含量进行分析,结果表明,3组高脂血症患者血清apoAl水平均明显降低,apoB及apoB/apoAl比值均明显升高;Ⅱa型高脂血症患者LDL-C明显升高,HDL-C无明显变化;Ⅱb型高脂血症患者LDL-C明显升高,HDL-C明显降低;Ⅳ型高脂血症患者HDL-C明显降低,LDL-C无明显变化;3组高脂血症患者LDL-C/HDL-C比值均明显升高。提示:高脂血症可使血清致动脉粥样硬化(As)因子升高和抗As因子降低,是As的危险因素之一。
The concentrations of serum aDoliDoprotein Al (aDo Al), aDo B and lipids of patients with 31 Ⅱa, 31 Ⅱb, 153 Ⅳ hyperlipemia and 100 normals were analysed. The results showed that serum aDO Al was significantly lower, aDo B and aDo B/aDO Al ratio were significantly higher in patients with hyperlipemia; that serum LDL-C was significantly higher but HDL-C has no significant change in patients with Ⅱ a type hyperlipemia; that serum LDL-C was significantly higher; HDL-C was significantly lower in patients with Ⅱ b type hyperlipemia; that serum HDL-C was significantly lower but LDL-C has no change in patients with Ⅳ type hyperlipemia; and that LDL-C/HDL-C ratio was significantly higher in three groups of hyperlipemia patients. It is suggested that hyperlipemia may cause increase of atherogenic factors and/or reduction of antiatherogenic factors, and is a risk factor of atherosclerosis.
出处
《安徽医科大学学报》
CAS
1992年第3期174-176,共3页
Acta Universitatis Medicinalis Anhui
基金
中华人民共和国卫生部青年科学研究基金。编号87-Y-068
