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血管内皮生长因子与肿瘤治疗 被引量:11

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摘要 血管内皮生长因子 (VEGF)是肿瘤血管新生的重要作用因子。在绝大多数恶性肿瘤中均呈现VEGF及其受体的高表达 ,从而形成旁 自分泌作用方式 ,促进内皮细胞分裂、增殖 ,诱导血管新生 ,并直接作用于肿瘤细胞 ,刺激肿瘤细胞生长。采用各种方法阻断VEGF与其受体的相互作用 ,可以阻断肿瘤血管新生 ,抑制肿瘤生长转移 。
作者 李容
出处 《国外医学(生理病理科学与临床分册)》 2002年第5期475-477,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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