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PKC亚型的生物学特性与调节功能 被引量:10

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摘要 PKC是细胞内信号转导的重要递质 ,迄今为止 ,已分离纯化至少 12种PKC亚型。有关PKC亚型与其它信息转导通路的关系、以及各亚型在细胞增殖、分化、凋亡等调节作用机制的研究 ,近年来都取得了突破性进展。针对在不同的细胞中PKC亚型的生物学效应和调节功能的差异 ,最终研制出高选择性PKC抑制剂 。
机构地区 大连医科大学
出处 《国外医学(生理病理科学与临床分册)》 2002年第5期493-496,共4页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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