1Anthonio Rl, Brouwer J, Lechat P,et al. Different effects of bisoprolol on heart rate in patients with ischemic oridiopathic dilated cardiomyopathy (a 24-hour holter substudy) of the Cardiac InsufficiencyBisoprolol Study[DIBIS]. Am J Cardiol, 1999, 83(8):1286.
2Kakuchi H, Sasaki T, Ishida-Y, et al. Clinical usefulness of 1231meta-iodobenzylguanidine imaging in predicting the effectiveness of beta blockers forpatients with idiopathic dilated cardiomyopathy before and soon after treatment. Heart,1999,81(2):148～152.
3Jansson K, Hagerman I,Ostlund R,et la. The effects of metoprolol and captopril onheart rate variability in patients with idiopathic dilated cardiomyopathy. Clin Cardiol,1999, 22(6):397～402.
4Toyama T, Aihara Y, Iwasaki T, et al. Cardiac sympathetic activity estimated by1231-MIBG myocardial imaging in patients with dilated cardiomyopathy after beta-blocker orangiotensin-converting enzyme inhibitor therapy. J Nucl Med,1999, 40(2):217～223.
5Santostasi G, Fraccarollo D, Dorigo P, et al. Early reduction in plasmanorepinephrine during beta-blocking therapy with metoprolol in chronic heart failure. JCard Fail, 1998, 4(3):177～184.
6Taegtmeyer H, Dietz GJ. Perspective: from increased energy metabolism to cardiachypertrophy and failure: mediators and molecular mechanisms. Am J Cardiol, 1999, 83:1H～2H.
7Kawai K, Takaoka H, Hata K, et al. Prevalence, predictors,and prognosis of reversalof maladaptive remodeling with intensive medical therapy in idiopathic dilatedardiomyopathy.Am J Cardiol, 1999, 84(6):671～676.
8Azuma A, Matsuc A, Nakamura T, et al. Improved survival of idiopathic dilatedcardiomyopathy in the 1990s. Jpn Circ J,1999, 63(5):333～338.
4Bridtow MR. What type of beta-blocker should be used to treat chronic heart failure[J]. Circulation ,2000,102(5) :484 - 486.
5Kim MH,Devlin WH, Das SK, et al.Effects of beta-adrenergic blocking therapy on left ventricular diastolic relaxation properties in patients with dilated cardiomyopathy[ J ]. Circulation, 1999,100(7) : 729 - 735.
6Metra M, Giubbini R, Nodari S, a d .Differential effects of betablockers in patients with heart failure: A prospective,randomized,double-blind comparison of the long-term effects of metoprolol versus carcvedilol[J].Circulation,2000,102(5):546-551
7McNeely W,Goakl. Nebivolol in the management of essential hypertension[J]. Drugs, 1999,57(4) : 633 - 651.
8Martijn AW,Pieteer A, Bas CAM, et al.Nebivolol:a Third-generation β-blocker that augments vascular nitric oxide release endothelial β2-Adrenergic receptor-mediated nitric oxide production[J]. Circulation, 2000,102 : 677 - 684.
9De Cree J, Van Rooy P, Geukens H, et al. The antihypetensive and cardiac hemodynamic effects of nebivolol[ J ].Angiology,1992,43 (5) : 369 - 377.
10Laeourciere Y, Poirier L, Lefebvre J. Comparative assessment of antihypertensive efficacy of DL-nebivolol and D-nebivolol in patients with confirmed mild to moderate hypertension[J] .J Cardiovasc Pharmacol, 1995,25(4) :619 - 624.
