肺炎衣原体与幽门螺杆菌混合感染在冠心病发病中的临床作用

Clinical Significance of Mixed Infection of Chlamydia Pneumoniae and Helicobacter Pylori for Onset of Coronary Heart Dis- ease

目的:探讨肺炎衣原体(CP)、幽门螺杆菌(HP)混合感染的相关性,了解CP、HP混合感染在冠心病(CHD)发病中的作用。方法:分别采用ABI胃幽门螺杆菌快速检测盒和微量免疫荧光法测定276例患者血清CP特异性抗体IgG(CPIgG)和HP特异性抗体IgG(HPIgG)。结果:CP、HP感染在致CHD的过程中存在正交互作用,二者混合感染使CHD的发病率升高,与二者单一感染相比,统计学上具有显著差异。结论:CP、HP感染在CHD的发病中起互相促进作用,二者混合感染时CHD的发病率较单一感染为高。

Objective:To investigate the relationship of the mixed infection of chlamydia pneumoniae (CP)and helicobacter pylori (HP) and inquire the effect of the mixed infection of the two kinds of pathogen on the onset of coronary heart disease (CHD) .Methods : The serum CP - specific IgG titers and HP - specific IgG liters were surveyed in 276 cases of patienls by use of quick detecler of ABI slomach helicobacter pylori and delicate microimmun fluoroassay. Results: During the process of causing CHD, the infection of CP and HP had plus mutual influence. The incidence of CHD caused by the mixed infection of the Iwo kinds of palhogen was higher than that caused by individual infection of any one kind of pathogen,and the difference was considerable in stalistics.Conclusion:The infection of CP and HP plays a mutual accelerating role in the onset of CHD. The incidence of CHD caused by the mixed infection of the two kinds of pathogen is higher than that caused by individual infection of any one of pathogen.