双向凝胶电泳和质谱技术在男性生殖医学研究中的应用
摘要
人类基因组计划已基本完成,包括蛋白质组时代的后基因组时代已经到来,蛋白质组研究旨在揭示基因组表达的真正执行生命活动的全部蛋白质的表达规律和生物功能。借助于蛋白质组研究的两种基本技术手段——双向凝胶电泳和质谱技术,阐明与男性生殖功能密切相关的蛋白质及其功能,必将有助于深入理解睾丸发育/精子发生的生理机制,揭示男性不育的发病机理,最终对男性生殖健康产生深远的影响。
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