鞘内注射芬太尼对硬膜外麻醉下剖宫产术中恶心、呕吐的抑制作用

Inhibiting effect of intrathecal fentanyl on intraoperative vomiting during cesarean delivery under epidural anesthesia

目的观察鞘内注射芬太尼对硬膜外麻醉下剖官产术中恶心、呕吐发生的抑制作用.方法将硬膜外麻醉下行剖官术产者30例(ASA分级Ⅰ～Ⅱ级)随机均分为对照组和芬太尼组,比较两组产妇术中出现恶心、呕吐的情况,并对娩出婴儿行Apgar评分.结果对照组与芬太尼组术中发生恶心者分别为5例(33.3%)和1例(6.7%);对照组呕吐或干呕发生率则显著高于芬太尼组(P＜0.05);两组娩出婴儿的Apgar评分无显著差异(P＞0.05).结论鞘内注射芬太尼能减少产妇硬膜外麻醉下剖宫产术中恶心、呕吐的发生.

Objective To observe the inhibiting ef fect of intrathecal (IT) fentanyl on nausea and vomiting during cesarean de-live ry under epidural anesthesia. Methods Thirty healthy parturients (ASA gradeⅠto Ⅱ) were randomly assigned in equal numbers into control and fentanyl groups (n =15 each, patients in the latter group treated with IT fentanyl at the dose of 2 0 ìg/ 3 ml). The incidence of nausea and vomiting during the elective cesarean deli very under epidural anesthesia between the 2 groups were compared and the neona tes' Apgar scores assessed after the delivery. Result Intraoperative nausea and vomiting/retching were reduced in the IT fentanyl group as compared with the co ntrol group (6.7% vs33.3% and 0 vs26.7%, P>0.05 and P<0.05 respectively). The n eonates' Apgar scores were not significantly different between the 2 groups (P>0 .05). Conclusion IT fen-tanyl can decrease intraoperative vomiting during cesare an delivery performed under epidural anesthesia.