摘要
目的 研究糙叶败酱 (PatriniascabraBunge)根中的化学成分。方法 用硅胶柱色谱技术进行分离纯化 ,根据理化性质和光谱数据进行结构鉴定。结果 从其脂溶性部位分离得到了 4个化合物 ,分别鉴定为十六烷酸 α 单甘油酯 (I)、齐墩果酸 (II)、槲皮素 (III)、N 苯甲酰基苯丙氨酸 2 乙酰胺基苯丙醇酯 (IV)。结论 所得化合物均为首次从该植物中分得 ,IV为一个新的生物碱 ,命名为糙叶败酱碱 (patriscabratine)。
AIM To study the chemical constituents of the roots ofPatrinia scabra Bunge. METHODS Various chromatographic techniques were used to separate and purify the constituents. Their structures were elucidated on the basis of chemical evidences and spectral analysis. RESULTS Four compounds were isolated from the roots ofP.scabra. They were identified as hexadecylic acid-α-monoglyceride (I), oleanolic acid (II), quercetin (III),N-benzoyl-phenylalanine-2-acetylamino-phenylpropanol easter (IV). CONCLUSION All compounds were isolated from this plant for the first time. Among them, IV is a new alkaloid and named patriscabratine.
出处
《药学学报》
CAS
CSCD
北大核心
2002年第11期867-869,共3页
Acta Pharmaceutica Sinica
关键词
糙叶败酱碱
分离
结构
鉴定
Patrinia scabra Bunge
alkaloid
patriscabratine