鼻咽癌310例疗效分析

RADIOTHERAPY OF NASOPHARYNGEAL CARCINOMA (Analysis of 310 cases)

本文报道我院1977年3月～1983年12月初次放射治疗的鼻咽癌病例共310例。5、10年生存率分别为26.1％(81/310)和20.6％(40/194)。本文讨论了影响预后的因素。临床分型上行型与下行型5年生存率无统计学差异,但上下行型最差。鼻咽原发灶肿瘤剂量以65～75Gy/6.5～7.5周为宜,颈部转移淋巴结最适宜治疗剂量为6.5～7.5Gy/6.5～7.5周,上行型患者应适当提高鼻咽灶剂量。

This paper reports 310 patients with nasopharyngeal carcinoma (NPC)treated in our hospital from March 1977 to December 1983. The 5 and 10-year survival rates were present in 26.1% and 20. 6% ,respectively. The factors influencing the prognosis were analysed. For stages Ⅰ , Ⅱ the 5-year survival rate was 76. 2%,while for stages Ⅲ , Ⅳ the rate was 22. 5%( P <0. 01). The prognosis of patients ascending(A) and descending (D)type of NPC showed no significant difference* but patients with mixed(AD)type NPC were associated with a poor prognosis. It is suggested that the optimum dose to the nasopharynx might be 65~75Gy/6. 5~7. 5wks,and that to the cervival region 65 ~ 76Gy/6. 5~7. 5wks. For patients ascending type, the optimum dose would be 70~ 80Gy/7~8wks.