摘要
The pharmacokinetics local model was used to evaluate renal function. Some typical kinds of renal function cases, normal or disorder, were selected to be imaged with SPECT and those data measured were treated by the pharmacokinetics local model computer program (PLM). The results indicated that parameters, including peak value, peak time, inflexion time, half-excretion time, and kinetic equation played and important role in judging renal function. The fact confirms that local model is very useful in evaluating renal function.
The pharmacokinetics local model was used to evaluate renal function. Some typical kinds of renal function cases, normal or disorder, were selected to be imaged with SPECT and those data measured were treated by the pharmacokinetics local model computer program (PLM). The results indicated that parameters, including peak value, peak time, inflexion time, half-excretion time, and kinetic equation played and important role in judging renal function. The fact confirms that local model is very useful in evaluating renal function.
基金
Natural Foundation of Jiangsu Province China
关键词
药物动力学
定域模型
肾功能
Renal function, Pharmacokinetics, Local model, SPECT
