人体对室内外空气污染物的暴露量与潜在剂量的关系

Relationship of Exposure and Potential Dose of Human Exposed to Indoor and Outdoor Air Pollutants

目的探讨人体对室内外空气污染物的暴露量(exposure)与潜在剂量 (potentialdose)的关系。方法分析并对比暴露量与潜在剂量的定义和计算方法 ;应用方案评价法分别计算个体对室内外空气中甲醛的暴露量与潜在剂量和对CO的暴露量与潜在剂量 ,并分析暴露量与潜在剂量的关系。结果与暴露量相比 ,潜在剂量能更好地反映通过呼吸进入人体内的污染物的量 ,对比室内外人体对甲醛和CO的暴露量和剂量 ,二者有时明显相关 ,有时无相关性。结论与暴露量相比 。

Objective To examine the relationship of exposure and potential dose of human exposed to indoor and outdoor air pollutants. Methods The definition and calculation methods of exposure and potential dose were analyzed and compared. Personal exposure and potential dose of formaldehyde and carbon monoxide in indoor and outdoor air were calculated by scenario evaluation approach respectively, and the relationships between exposure and potential dose were analyzed also. Results Potential dose could much better accurately reflect the amount of air pollutants entering human body through respiratory tract than exposure did. Exposures and potential doses of human exposed to formaldehyde and carbon monoxide in indoor and outdoor air were significantly correlated in some cases, but not correlated well in other cases. Conclusion Potential dose might be more accurately linked to health effects of air pollutants than exposure did.