干扰素联合中药治疗慢性乙型肝炎的研究

Study on the therapy of chronic hepatitis B with interferon and traditional Chinese medicine

目的 探讨干扰素联合中药治疗慢性乙型肝炎的疗效。方法 将 12 0例HBeAg及HBVDNA均为阳性的慢性乙型肝炎病人随机分为两组 ,治疗组 6 0例 ,使用干扰素及中药 ;对照组 6 0例 ,仅使用干扰素。3个月为 1个疗程。结果 疗程结束后治疗组ALT值、HBeAg及HBVDNA转阴率分别为 4 5 6± 2 1 6U/L、6 3 3% (38/ 6 0 )、70 % (4 2 / 6 0 ) ,与对照组比较差异有显著意义 (P <0 0 5 )。结论 治疗慢性肝炎时 。

Objective To explore the curative effect of interferon and traditional Chinese medicine(TCM) on chronic hepatitis B.Methods Onehundred and twenty cases of chronic hepatitis B patients with positive HBeAg and HBV DNA were divided into two groups(60 patients each group),treated with interferon combined with traditional Chinese medicine in theraputic group and only with interferon in control group respectively.One course of treatment was three months.Results After one course of treatment,in theraputic group,the value of ALT and the rate of transformation of HBeAg and HBV DNA were 45.6±21.6 U/L and 63.3%(38/60),notablly different from that in control group(P<0.05).Conclusion The traditional Chinese medicine is beneficial to enhance the curative effect on curing chronic hepatitis B with interferon.