早产和小样儿与孕妇血浆血红蛋白关系的研究

Relationship between the hemoglobin level during pregnancy and preterm birth and small for gestational age

目的 研究孕妇血浆血红蛋白水平与早产和小样儿 (SGA)之间的关系。方法 回顾性研究80 7例孕妇血红蛋白水平与不良妊娠后果之间的关系。结果 妊娠第一和第二周期 (第一和第二个 3个月 )血红蛋白降低则早产的危险性增高 ,贫血与SGA无关 ;第一和第二周期血红蛋白增高与SGA有关 (OR值分别为 1 2 8、1 79) ,而与早产无关。结论 在评估不良妊娠后果时要充分考虑到贫血和高血红蛋白水平的影响 ;

Objective To study the association of maternal hemoglobin during pregnancy with preterm birth and small for gestational age(SGA).Methods The association between maternal hemoglobin and birth outcome was studied by means of retrospective cohort analysis.Results Risk of preterm birth was increased in women with low hemoglobin level in the first and second trimester.Anemia was not associated with SGA.High hemoglobin level during the first and second trimester was associated with SGA but not preterm birth.The odds ratios(ORs) for SGA in women with very high hemoglobin level during the first and second trimester were 1.28 and 1.79 respectively.Conclusion These data highlight the importance of considering anemia and high hemoglobin level as indicators for adverse pregnancy outcomes.Iron supplement is advised for preventing preterm birth.