内镜下胰腺细胞学检查方法对胰腺肿瘤的诊断价值

Value of cytologic examination under the endoscope in the diagnosis of pancreatic tumors.

目的 探讨内镜下胰腺细胞学检查对胰腺肿瘤诊断的临床应用价值 ,提高对胰腺恶性肿瘤的检出率。方法 在ERCP检查的同时采用胰管细胞刷及放置鼻胰管方法对 47例患者进行研究。结果 刷检细胞学检查准确性为 70 4% ,敏感性为 65 2 % ,特异性为 10 0 % ;胰液细胞学准确性为 45 % ,敏感性为 8 3 %及特异性10 0 %。结论 该检查方法快速 ,经济实用 ,安全和准确性高 ,不失为胰腺肿瘤早期诊断的一种可靠且有价值的检查手段。

Objective To evaluate the usefulness of cytologic examinations in the diagnosis of pancreatic neoplasms using nasopancreatic drainage and pancreatic duct brushing during ERCP.Methods In 47 patients with pancreatic diseases,cytologic examinations of pancreatic duct brushing and nasopancreatic drainage during ERCP were performed.Results The rate of accuracy,sensitivity,and specificity of brush cytologic examination were 70\^4%,65\^2% and 100%,respectively,and that of pancreatic juice cytologic examinations was 45%,8\^3% and 100%,respectively.Conclusion Our results confirm the value,safety,and utility of obtaining cytologic specimens at the time of ERCP for the early diagnosis of pancreatic neoplasms.