血清及腹水CA_(125)对结核性腹膜炎的诊断价值

Significance of serum and ascites CA_(125) in the diagnosis of tuberculous peritonitis.

目的 探讨糖抗原1 2 5(CA1 2 5)对结核性腹膜炎诊断价值。方法 应用酶微粒子法测定结核性腹膜炎和肝硬化患者的血清、腹水CA1 2 5水平及正常人血清CA1 2 5水平。应用腹膜多功能检查针取腹膜活检。结果 CA1 2 5>60 0kU/L中 ,结核性腹膜炎血清、腹水阳性例数分别为 2 / 2 0、5 / 2 0 ;肝硬化血清、腹水阳性例数分别为 2 /2 0、3 / 2 0。CA1 2 5<60 0kU/L中 ,结核性腹膜炎血清、腹水分别为 (10 3 42± 68 2 8)kU/L、(4 4 4 82± 68 95 )kU/L ;肝硬化血清、腹水分别为 (63 3 8± 3 7 0 0 )kU/L、(2 2 4 60± 79 3 9)kU/L ;正常对照血清为 (2 4 5 1± 8 5 1)kU/L。结论 CA1 2

Objective To investigate the significance of serum and ascites CA 125 in the diagnosis of tuberculous peritonitis.Methods The levels of CA 125 were observed in serum and ascites in patients with tuberculous peritonitis or liver cirrhosis and controls.The pathological diagnosis was made by peritoneal biopsy using multiple peritoneal biopsy needle.Results In CA 125 >600kU/L group,10%(2/20) of patients suffering from tuberculous peritonitis were positive in the serum test,while 25%(5/20)in ascites,while in liver cirrhosis,the positive rate was 10%(2/20)in serum and 15%(3/20)in ascites.In CA 125 <600kU/L group,the values of CA 125 in serum and ascites were (103 42±68 28)kU/L and (444 82±68 95)kU/L in tuberculous peritonitis respectively,and in liver cirrhosis,the values were (63 38±37 00)kU/L and (224 60±79 39)kU/L.In the controls,the value was(24\^51±8\^51)kU/L.Conclusion CA 125 can be a marker for the diagnosis of tuberculous peritonitis.