成纤维细胞生长因子10在前列腺增生组织中的表达

The significance of fibroblast growth factor 10 mRNA expression in benign prostate hyperplasia tissue

目的 检测前列腺增生组织中成纤维细胞生长因子 10(FGF 10 )的表达 ,探讨其在前列腺增生中的作用。方法 应用半定量RT PCR技术和免疫组织化学方法 ,检测 2 0例前列腺增生组织中FGF 10的表达 ,并与正常的前列腺组织进行比较。结果 前列腺增生组织中FGF 10mRNA的水平高于正常前列腺组织 ;前列腺组织中均见FGF 10阳性染色 ,前列腺增生组织中表达显著高于正常的前列腺组织。结论 前列腺增生组织中FGF 10的表达高于正常前列腺组织 ,提示FGF

Aim To determine expression of fibroblast growth factor 10 (FGF 10) in benign prostate hyperplasia tissue. Methods The expression levels of FGF 10 mRNA in benign prostate hyperplasia and normal prostate tissues were detected by semi quantitive RT PCR, while the expression level of FGF 10 protein were detected by immunohistochemcal staining and quantitative analysis. Results The expression levels of both FGF 10 mRNA and protein in benign prostate hyperplasiatissue were higher than those in normal prostate tissues. Conclusion FGF 10 may play an important role in benign prostate hyperplasia tissue.