冠状动脉瘤样扩张与电子束CT检测的冠状动脉钙化

Coronary Artery Ectasia and Coronary Artery Calcification Detected by Electron Beam Computed Tomography

为探讨冠状动脉瘤样扩张患者电子束CT检测的冠状动脉钙化的特点及其临床和病理意义 ,将 2 7例经选择性冠状动脉造影确诊的冠状动脉瘤样扩张患者行电子束CT检查以计算钙化积分 ,并与 2 7例年龄和性别匹配的冠状动脉造影正常者进行比较。结果发现 ,冠状动脉瘤样扩张组钙化阳性率、钙化积分中位数及钙化积分的自然对数转换值均显著高于正常对照组 (P <0 .0 1或 0 .0 0 1)。冠状动脉瘤样扩张组中 2 1例粥样硬化性瘤样扩张患者钙化阳性率为 81.0 % ;弥漫性扩张动脉的钙化积分对数转换值显著低于局限性扩张动脉 (1.2 2± 1.79比 2 .86± 1.85 ,P <0 .0 5 )。结果提示 ,粥样硬化性冠状动脉瘤样扩张患者多数存在较为广泛的冠状动脉钙化 ,且钙化程度与病变类型有关。

Aim To investigate the features of coronary artery calcification (CAC) determined by electron beam computed tomography (EBCT) in patients with coronary artery ectasia. Methods In 27 patients who were diagnosed as coronary artery ectasia by coronary angiography, EBCTs were performed for calculating calcium score (CS). The calcium scores were compared between patients and angiographically normal subjects matched for sex and age. Results The CAC prevalence, CS median and LN (the mean natural logarithm transformation of calcium score) were all greater in ectasia group than in control group (P<0.01 or 0.001). Coronary artery calcification existed in 17 of the 21 patients with atherosclerotic coronary artery ectasia (81.0%). The mean LN was significantly lower in vessels with diffuse ectasia than in those with discrete ectasia (1.22±1.79 vs 2.86±1.85, P<0.05). Conclusion Coronary artery calcification exists in most of the patients with atherosclerotic coronary artery ectasia, and the extent of calcium is related to the types of ectasia.