摘要
b Institute of Chemistry, Academia Sinica, Taipei, Taiwan 11529, China One pot hydroiodination and deconjugation of 5 aryloxy(or thiophenyl) 3 pentyn 2 one with a reagent system of sodium iodide/trimethylsilyl chloride/water in acetonitrile at 25 ℃ have been described. The plausible mechanism was discussed. The reaction provided a simple and useful method for the preparation of ( Z ) β substituted β,γ enones and ( Z ) β substituted α,β unsaturated ketones.
b Institute of Chemistry, Academia Sinica, Taipei, Taiwan 11529, China One pot hydroiodination and deconjugation of 5 aryloxy(or thiophenyl) 3 pentyn 2 one with a reagent system of sodium iodide/trimethylsilyl chloride/water in acetonitrile at 25 ℃ have been described. The plausible mechanism was discussed. The reaction provided a simple and useful method for the preparation of ( Z ) β substituted β,γ enones and ( Z ) β substituted α,β unsaturated ketones.
基金
theScienceCouncilandAcademiaSinicaofTaiwan China
