痔克胶囊的研制与临床应用

Preparation and Clinical Use of Zhike Capsules

目的 :研制以壁虎为君药的痔克胶囊 ,观察其临床疗效。方法 :制定制备工艺及质量标准 ,观察 63例痔疮患者口服该方的疗效。结果 :该药采用薄层层析法鉴别君药 ,方法简便可行。含量测定方法平均回收率 99.6% ,RSD2 .18%。Ⅰ期内痔显效率 10 0 .0 % ,Ⅱ期内痔 62 .5 % ,Ⅲ期内痔 40 .0 %。结论 :该药组方合理 ,质控方法可靠 ,疗效显著。

Objective:To prepare zhike capsules in which gecko is the main drug and observe their clinical curative effect. Method:The preparation technology and quality standards of zhike capsules were formulated, and the curative effects were observed by treating 63 cases of piles patients who took them orally. Results:The method to distinguish the main drug by thin-layer chromatography (TLC) was simple and practicable. The average recovery of content determination was 99.6%, and the relative standard deviation ( RSD ) was 2.18%.The effective rates of phaseⅠ, phaseⅡ and phaseⅢ internal piles were 100.0%, 62.5% and 40.0% respectively. Conclusion:The recipe of zhike capsules is reasonable, the methods to control quality are reliable and the curative effects are obvious.