北京部分地区一般人群中幽门螺旋菌血清抗体的流行病学调查

Eptdemdololgic Investigation on Helicobactsia Pyloroas Serum Antibody Level of the Common People in a Part of Beijing Districts

本文应用ELISA法对北京部分地区一般人群的血清幽门螺旋菌抗体水平进行了流行病学调查。发现抗体水平随年龄的增加而升高,60岁以上老人抗体阳性率达66.2%,而2l～30岁年龄组仅为27.1%;这恰与胃炎随年龄升高而发病率上升的现象相一致。在是否吸烟和饮酒的问题上,未见血清抗体水平有明显差异(P>0.05)。调查表明:幽门螺旋菌感染是本地区人群胃炎的病因之一;本地区人们一生中反复遭受幽门螺旋菌感染,从而造成随年龄升高感染率上升之现象。而吸烟和饮酒不影响幽门螺旋菌对人体之感染。

The helicobacteria pylori (HP) serum antibody level of common people inapart of Beijing districts was investigated with ELISA method. We found that the level of HP antibody was increased in parallel with the age of people. The positive rate of HP antibody of people above 60years old was 66.2%, while 21 to 30 years old persons only had 27.1% of HP antibody positive rate. This tendency is very similar to the incidence of chronic gastritis, the incidence of the latter is increased with the increasing of the years of age. Smoking and alcohol-drinking did not effect the level of HP antibody (P>0.05). The resuits suggest that: persons in this area would have often been attacked by HP all the life time; HP was one of the main causes of gastritis; Smoking and alcohol-drinking did not effect the HP infection of persons.