摘要
目的通过动物实验研究羊膜移植联合对侧健眼穹隆部结膜移植治疗单眼重症化学烧伤所致睑球粘连的疗效.方法 将两组实验动物家兔单眼制成重度碱烧伤模型,实验组患眼施行角膜缘白体移植、羊膜移植联合对侧健眼穹隆部结膜移植,对照组患眼仅施行角膜缘自体移植、羊膜移植。于术前、碱烧伤后1个月、术后3个月分别行眼表面印痕细胞学检查和病理学检查。 结果 实验组睑球粘连缓解明显优于对照组,睑球粘连缓解病例术后3个月羊膜表面皆有上皮细胞长入。结论 羊膜移植联合对侧健眼穹隆部结膜移植对睑球粘连及大面积结膜缺损有效,且优于单纯羊膜移植。
Objective To observe the effects of human amniotic membrane transplantation combined with contralateral fornical conjunctiva transplantation on treatment of unilateral symblepharon secondary to severe chemical burns. Methods Experiment animals were divided into two groups randomly. Limbal autografts, human amniotic membrane transplantation and contralateral healthy fornical conjunctiva transplantation were performed on diseased eyes of experimental group. Limbal autografts and human amniotic membrane transplantation were performed on rabbits of control group. In one month after chemical burns and three months after surgery .impression cytology study was performed. The observation of surgical results and histopathologic were done in three months after surgery. Results The symblepharon in experimental group was evidently ameliorated compared with control group. All of the eyes in two groups were reepithelialized on human amniotic membrane surface in three months after surgery. Conclusions Human amniotic membrane transplantation combined with contraiateral healthy fornieal conjunctiva transplantation is benifical to the recovery of damaged conjunctival epithelium.
出处
《眼科研究》
CSCD
北大核心
2002年第6期491-494,共4页
Chinese Ophthalmic Research
