摘要
除神经营养素家族外 ,多种细胞因子通过受体介导神经元存活。细胞因子主要激活PI3K AKT和Raf MEK Erk1/
Besides neurotrophins, several cytokines promote neuronal survival mainly by PI3K AKT and Raf MEK Erk1/2 signaling cascades, which result in phosphorylating pro apoptotic protein to suppress apoptosis and activating transcription factor to induce expression of neuronal survival related gene.
出处
《创伤外科杂志》
2002年第B12期49-51,28,共4页
Journal of Traumatic Surgery
基金
国家自然科学基金课题 (NO39870 835 )