洁肤净洗剂的抗菌、抗滴虫、止痒及抗炎作用

Antibacterial, antitrichomonal, antipruritic and anti-inflammatory effects of Jiefujing Lotion

目的 :研究洁肤净洗剂 (黄连 ,黄柏 ,蛇床子 ,地呋子和当归 )的抗菌、抗滴虫、止痒、抗炎作用。方法 :采用体内、外抗菌法、体外抗阴道滴虫法、豚鼠组胺致痒阈法、大鼠和小鼠蛋清及二甲苯致炎法。结果 :洁肤净洗剂对与生殖器官炎症有关的细菌和真菌有不同程度的抑制和杀灭作用 ,对阴道滴虫有杀灭作用 ,能提高豚鼠组胺致痒阈 ,并有抗炎作用。结论 :洁肤净洗剂具有明显的抗菌、抗滴虫。

Objective: To observe the antibacterial, antitrichomonal, antipruritic and anti inflammatory effects of Jiefujing Lotion(Rhizoma Coptidis, cortex Phellodendri, Fructus cnidii Fruetus Kochiae, Radix Angelicae Sinensis, etc). Methods: The methods were applied antibacterial in vivo and in vitro , vaginal trichomoniasis resistant in vitro , itch threshold of guinea pigs caused by histamine, rats and mouse inflammation caused by albumen and dimethylbenzene. Results: Jiefujing Lotion had considerable inhibitory and disinfecting activities to bacteria and fungus related to edeitis. The lotion could also kill vaginal trichomonads, increase the itch threshold value and had anti inflammatory effect. Conclusion: Jiefujing Lotion had obvious antibacterial, antitrichomonal, antipruritic and anti inflammatory effects.