非血红素N_4配体Mn(Ⅲ)配合物催化烯烃的不对称环氧化反应

Mn(Ⅲ) Complex Bearing Non-heme N_4 Ligand for the Asymmetric Epoxidation of Olefins

利用Mn(OAc)3与手性四氮配体制备了非血红素N4配体的Mn(Ⅲ)配合物,并将其应用于催化α,β-不饱和烯酮和简单烯烃的不对称环氧化反应,考察了氧化剂H2O2的量和添加剂HOAc的量等条件对反应结果的影响,研究了该催化剂的底物适用范围,获得了51%~94%的ee值.

A Mn(Ⅲ) complex bearing non-heme N4ligand was synthesized with Mn( OAc)3as a metal precursor,and successfully applied to asymmetric epoxidation of α,β-unsaturated ketones and simply olefins. The amount of oxidant,additive and other conditions were examined,then the scope of substrates under the optimized conditions were tested and ee values were obtained in the range of 51% ~ 94%.