急性有机磷农药中毒致呼吸衰竭急性有机磷农药中毒致呼吸衰竭:42例报告

42 cases analysis of acute organophosphorus pesticide poisoning with respiratory failure

目的探讨急性有机磷农药中毒呼吸衰竭的发生及诊治,提高临床抢救水平。方法对42例急性有机磷农药中毒患者进行临床分析总结。结果治愈36例,死亡4例,病死率9.52%,其中采用连续性肾脏替代治疗(CRRT)的6例患者无1例死亡。结论提高呼吸衰竭救治率成功的关键在于防止呼吸肌麻痹,强调以机械通气辅助呼吸和CRRT为主的综合治疗。

Objective To investigate the occurrence and treatment of acute organophosphorus pesticide poisoning with respiratory failure, improve the level of clinical emergency. Methods 42 cases of acute organophosphorus pesticide poisoning were analyzed and summarized the clinical. Results Cured 36 cases, 4 deaths, mortality 9.52%, which use continuous renal replacement therapy(CRRT) in 6 patients without a death. Conclusions Increased rate of respiratory failure, the key to successful treatment is to prevent respiratory muscle paralysis, the emphasis on mechanical ventilation and CRRT combined therapy.