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肝脂酶基因多态性是1型糖尿病男性患者高密度脂蛋白水平及其颗粒大小的主要决定因素(79—OR) 被引量:1

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出处 《国外医学(内分泌学分册)》 2002年第6期407-407,共1页 Foreign Medical Sciences(Section of Endocrinology)
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  • 1李宏义,鄢盛恺,严晓伟.汉族人肝脂酶基因启动子-514C/T多态性与2型糖尿病合并冠心病的关系[J].中华检验医学杂志,2005,28(4):373-377. 被引量:3
  • 2姚友权,徐力辛,熊术道.肝脂酶基因-514C/T变异对血脂的影响[J].蚌埠医学院学报,2007,32(4):431-434. 被引量:1
  • 3Zambon A,Deeb SS,Pauletto P,et al. Hepatic lipase:a marker for cardiovascular disease risk and response to therapy[J]. Curr Opin Lipidol,2003,14 (2) : 179-189.
  • 4Pihlajamaki J, Karijainen L, Karhapaa P, et al. G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia[ J]. Arterioscler Thromb Vasc Biol,2000,20(7) :1789-1795.
  • 5Jansen H,Waterworth DM,Nicaud V,et al. Interaction of the common apolipoprotein C-Ⅲ ( APOC3 -482C > T) and hepatic lipase (LIPC -514C > T) promoter variants affects glucose tolerance in young adults. European Atherosclerosis Research Study Ⅱ ( EARS- Ⅱ) [J]. Ann Hum Genet,2001,65(3) :237-243.
  • 6Yabu Y,Noma K,Nakatani K,et al. C-514T polymorphism in hepatic lipase gene promoter is associated with elevated triglyceride levels and decreasing insulin sensitivity in nondiabetic Japanese subjects[J]. Int J Mol Med,2005,16(3) :421-425.
  • 7Gomez P, Perez-Jimenez F, Marin C ,et al. The -514 C/T polymorphism in the hepatic lipase gene promoter is associated with insulin sensitivity in a healthy young population [ J ]. J Mol Endocrinol, 2005,34(2) :331-338.
  • 8Zambon A, Deeb SS, Hokanson JE, et al. Common variants in the promoter of the heptic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 choleaterol [ J ]. Arterioscler Thomb Vasc Biol, 1998, 18 ( 11 ) : 1723 -1729.
  • 9Todorova B, Kubaszek A, Pihlajamaki J, et al. The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study [ J ]. J Clin Endoerinol Metab,2004, 89(5) :2019-2023.
  • 10Deeb SS,Zambon A, Ayyobi AF, et al. Hepatic lipase and dyslipidemia :interactions among genetic variants, obesity, gender, and diet[J]. J Lipid Res,2003,44(7) :1279-1286.

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