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重型脑外伤超微结构的观察与预后关系的研究 被引量:2

Study on the Relationship between the Observation and the Fine Structure of Severe Cerebral Trauma and Its Prognosis
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摘要 目的 通过对重型脑外伤脑白质的超微结构的观察及临床分析 ,比较单纯性脑挫伤与脑挫伤合并弥漫性轴索损伤 (DAI)患者的预后差异。方法 随机选择 2 8例GCS 8分以下 ,CT显示有脑挫伤、挫伤性血肿 ,需手术治疗的病例 ,术中取非功能区皮质下肉眼观无挫伤的白质 0 .5cm× 0 .5cm× 0 .5cm大小 ,电镜观察 ,并进行临床资料分析。结果  2 8例观察标本中 ,10例伴有不同程度DAI ,其病死率和致残率较其他病例明显高。结论 ①脑挫伤、挫伤性血肿伴有DAI病例的预后比单纯脑挫伤差 ,病死率和致残率高。②脑挫裂伤患者如原发性昏迷时间长 ,手术后意识不能好转应考虑合并DAI。 Objective\ To compare the prognostic differences among patients with cerebral contusion and the complication of diffuse axonal injury (DAI) through observations and clinical analyses of the fine structure of white matter of brain in severe cerebral trauma. Methods\ 28 cases of severe cerebral trauma (GCS<8) were chosen randomly. Cereboal contusion and hematomas were indicated by CT examinations and operations were needed. White matter of 0.5 cm×0.5 cm×0.5 cm in size of non contusion observed with naked eye was taken from subcortex and observed by an electron microscope. Clinical data were analysed. Results\ 10 of the 28 cases had DAI to varying degrees, whose mortality and crippling rate were obviously higher than those of the other cases.Conclusion\ The patients with cerebral contusion may suffer from DAI if they have a long time of primary coma and cannot completely recover consciousness after operation.
作者 李真保
出处 《皖南医学院学报》 CAS 2002年第4期266-268,共3页 Journal of Wannan Medical College
基金 院中青年科研基金 (编号YK2 0 0 0 12 )资助
关键词 脑损伤 弥漫性轴索损伤 显微镜检查 电子 预后 brain injuries diffuse axonal injury (DAI) fine stracture microscopy,election prognosis
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