人体左心室复合材料有限元机械模型的建立

CONSTRUCTION OF THREE DIMENSIONAL COMPOSITE FINITE ELEMENT MECHANICAL MODEL OF HUMAN LEFT VENTRICLE

人体心脏通过电兴奋引起的心肌收缩实现泵血功能 ,而心肌的力学特性高度依赖于肌纤维旋向。根据肌纤维结构和复合材料理论建立了人体左心室的三维有限元机械模型 ,并讨论了心电兴奋力及后负荷的计算问题 ,最后仿真研究了在正常心脏兴奋传播过程中左心室在载荷作用下的力学响应 ,并与磁标记的MR成像结果及其他有关模型进行了比较。研究结果表明该模型可用于探讨心脏的机械功能和生理病理机制 。

The human heart pumps blood via contraction of myocardial fibers, and the mechanical properties of the muscle depend highly on its fibrous structure. Considering the fiber orientation, a three dimensional finite element mechanical model of left ventricle was constructed based on composite theory, and the computing issues of the active force and afterload were discussed. Finally the mechanical response of the left ventricle subjected to the normal excitation propagation process was simulated and the results were compared with those obtained from MR tagging images and those coming from other models. It proved that our model can be used to study the mechanical function of the left ventricle, and it laid a good foundation for construction of virtual heart with electrophysiological and mechanical properties.