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人类个体发育中的免疫球蛋白重链可变区基因谱型

Development of human immunoglobulin heavy chain gene repertoire
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作者 毛晓健
机构地区 广州市儿童医院
出处 《中国当代儿科杂志》 CAS CSCD 2002年第5期424-426,共3页 Chinese Journal of Contemporary Pediatrics
关键词 人类 个体发育 免疫球蛋白重链 可变区基因谱型
分类号 R392 [医药卫生—免疫学]
  • 相关文献

参考文献15

  • 1Cook GP, TomlinsonI M, Walter G, et al. A map of the human immunoglobulin Vh locus completed by analysis of the telomeric region of chromosome 14q [J]. Nature Genet, 1995, 7(2): 162-168.
  • 2Cuisinier AM, Guigou V, Boubil L, et al. Preferential expression of VH5 and VH6 immunobulin genes in early human B-cell ontogeny [J]. Scand J Immunol, 1989, 30(4): 493-497.
  • 3Cuisinier AM, Boubli L. Mechanisms that generate human immuonbulin diversity operate from the 8-week of gestation in fetal liver [J]. Eur J Immunol, 1993, 23(1): 110-118.
  • 4Schroeder HW, Wang JY. Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life [J]. Proc Natl Acad Sci USA, 1990, 87(16): 6146-6150.
  • 5Jeffrey E, Berman, Katherine G, et al. VH gene usage in humans:biased usage of the VH6 gene in immature B lymphoid cells [J]. Eur J Immunol, 1991, 21(5): 1311-1314.
  • 6肖昕,熊爱华,周晓光.早产儿与足月儿免疫球蛋白重链可变区基因异型性[J].中国优生与遗传杂志,2000,8(2):13-15. 被引量：1
  • 7肖昕,周晓光,熊爱华.新生儿有限的免疫球蛋白重链可变区基因多样性[J].中国当代儿科杂志,2000,2(3):129-131. 被引量：1
  • 8肖昕,周晓光,熊爱华.不同胎龄新生儿免疫球蛋白重链基因CDR3序列特征[J].中华微生物学和免疫学杂志,2001,21(3):267-271. 被引量：3
  • 9Hung SC, Ronghua J, Annuska M, et al. Non-stochastic utilization of IgV region genes in unselected human peripheral B cells [J]. Mol Immunol, 1996, 33(6): 553-560.
  • 10Braun J, Berberian L, King L, et al. Restricted use of fetal VH3 immunoglobulin genes by unselected B cells in the adult [J]. J Clin Invest, 1992, 89(5): 1395-1402.

二级参考文献22

  • 1王琰,刘群英,徐建军,王雅明,陈竞华.人抗-HBs Fab段基因的序列分析及表达[J].中华微生物学和免疫学杂志,1995,15(5):304-307. 被引量：27
  • 2Tonegawa S. Somatic generation ofantibody diversity. Nature, 1983.302:575-581.
  • 3Martin F, Chen X, Shu F, et al. Development of the mouse B-cell repertoire. Ann N YAcad Sci, 1995; 764:207-221.
  • 4Kepler TB, Borrero M, Rugerio B, et al. Interdependence of N nucleotide additionand recombination site choice in V(D)J rearrangement. J Immunol, 1996;157: 4451-4457.
  • 5Neuberger MS, Milstein C. Somatic hypermutation. Curr Opin Immunol, 1995.7:248-254.
  • 6Choi Y, Rickert MH, Ballow M, et al. Human IgH-V gene repertoire in neonatal cordblood, adult peripheral bolld and EBV-transformed cell. Ann NY Acad Sci, 1995,261:764-767.
  • 7Cuisinier AM, Guigou V, Boubli L, et al. Preferential expression of VH5 and VH6immunoglobulin genes in early human B-cell ontogeny.Scand J Immunol, 1989, 30:493-497.
  • 8Stollar BD. The expressed heavy chain V gene repertorire of circulating B cells innormal adults. Ann N Y Acad Sci, 1995;764:265-274.
  • 9Sun J, Hayward C, Shinde R, et al. Antibody repertoire development in fetal andneonatal piglets. l. Four VH genes account for 80 percent of VH usage during 84 days offetal life. J Immunol, 1998;161:5070-5078.
  • 10Feeney AJ. Lack of N regions in fetal and neonatal mouse lg V-D-J junctionalsequences. J Exp Med, 1990,172:1377-1390.

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中国当代儿科杂志
2002年 第5期

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