乙嘧硫磷的合成研究

The Synthesis of Etrimfos

以丙腈为初始原料 ,经四步反应 ,在国内首次合成了高效低毒的有机磷杀虫剂 -乙嘧硫磷 ,并对乙嘧硫磷及其各个中间体丙脒盐酸盐、2 -乙基 - 4 ,6 -二羟基嘧啶、2 -乙基 - 4 -乙氧基- 6 -羟基嘧啶进行了定性、定量分析。反应总收率 5 0 7%。

Etrimfos,a high efficiency and low-toxic organic phosphorus insecticide, was synthesized by four-step reaction process from propionitrile as starting materials firstly at home And these intermediates of etrimfos, which are propionamidine hydrochloride,2-ethyl-4,6-dihydroxypyrimidine and 2-ethyl-4-ethoxy-6-hydroxypyrimidine,are quantitatively and qualitatively analyzed The total yield of the whole reaction is 50 7%