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甘麦大枣汤干预多种抑郁症的疗效及药理探究 被引量:40

Efficacy and Pharmacological Exploration of Ganmai Dazao Decoction Intervening in a Variety of Depression
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摘要 甘麦大枣汤源自《金匮要略》,是古今治疗精神科疾病的名方,药味数量精简,但是临床效果显著。具有安神除烦,养心解郁,补脾和中,柔肝缓解等功效。由于中医无抑郁症病名,而抑郁症的症状与失眠、脏躁等类似,临床常用治疗脏躁证的方剂甘麦大枣汤治疗抑郁症及其他多种心身疾病。现整理了近年来关于甘麦大枣汤的临床研究及现代药理学实验研究资料,发现该汤剂治疗多种抑郁症有效,为临床用药提供参考。 Ganmai Dazao Decoction is from the Essentials from the Golden Cabinet.It is a famous prescription for the treatment of psychiatric diseases in the ancient and modern times.The prescription form is concise but the clinical efficacy is remarkable.It has the effects of calming the mind and eliminating dysphoria,nourishing heart and relieving depression,nourishing spleen and harmonizing the center,softening liver and relieving,etc.Due to the absence of the name for depression in traditional Chinese medicine,and the symptoms of depression are similar to insomnia,visceral agitation and so on,Ganmai Dazao Decoction is often used as a formula for treating visceral agitation to treat depression and other psychosomatic diseases in clinic.We compiled the clinical research and modern pharmacology experiment data of Ganmai Dazao Decoction in recent years.The results show that this decoction is effective for the treatment of various depression and provide reference for clinical medication.
作者 庄红艳 贾竑晓 刘杰 尹冬青 冯秀杰 薛春苗 Zhuang Hongyan;Jia Hongxiao;Liu Jie;Yin Dongqing;Feng Xiujie;Xue Chunmiao(National Center for Clinical Medical Research of Mental Disorders&Beijing Key Laboratory for Diagnosis and Treatment of Mental Disorders,Beijing Anding Hospital Affiliated to Capital Medical University,Beijing 100088,China;Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing 100069,China;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)
出处 《世界中医药》 CAS 2019年第7期1907-1910,1914,共5页 World Chinese Medicine
基金 首都卫生发展科研专项重点攻关项目(首发2018-1-2122) 北京市科委“首都临床特色应用研究”专项(Z151100004015061) 首都医科大学基础与临床合作课题(16JL84) 北京中医药科技发展基金项目(JJ2018-42)
关键词 甘麦大枣汤 《金匮要略》 脏躁 抑郁症 躯体疾病共病 临床研究 药理学 Ganmai Dazao Decoction Essentials from the Golden Cabinet Visceral agitation Depression Somatic disease comorbid depression Clinical study Modern pharmacological research
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