胺碘酮联合倍他乐克治疗急性室性心律失常的效果分析

Effect of Amiodarone Combined with Betaloc on Acute Ventricular Arrhythmia

目的探讨急性室性心律失常患者给予应用胺碘酮与倍他乐克联合治疗的效果评价。方法方便选择2017年10月—2018年10月该院收治的100例急性室性心律失常患者纳入该次研究工作,按照数字随机表法将其划分成2组,分别命名为试验组(n=50)与对照组(n=50)。对照组接受胺碘酮单一,试验组接受胺碘酮与倍他乐克联合治疗。比较两组患者并发症发生率、治疗前后血压、心率变化情况、生活质量、治疗效果。结果治疗前两组患者生活质量评分比较差异无统计学意义(P>0.05),治疗后试验组生活质量评分高于对照组评分,组间数据对比差异有统计学意义(P<0.05);试验组治疗总有效率49例(98.00%)高于对照组40例(80.00%)(χ^2=8.273 7,P=0.004 0),数据对比差异有统计学意义(P<0.05);两组患者治疗前舒张压、收缩压、心率等对比差异无统计学意义(P>0.05),治疗后试验组舒张压与收缩压均低于对照组,心率次数少于对照组,组间对比差异有统计学意义(P<0.05);试验组并发症总发生率2例(4.00%)低于对照组11例(22.00%),组间对比差异有统计学意义(P<0.05)。结论针对急性室性心律失常采取胺碘酮与倍他乐克联合治疗,其临床效果显著,可全面稳定患者临床各项指标,降低其并发症发生率,临床治疗安全性较高。

Objective To evaluate the effect of combined treatment with amiodarone and betaloc in patients with acute ventricular arrhythmia. Methods One hundred patients with acute ventricular arrhythmia admitted from October 2017 to October 2018 were conveniently selected in the study. They were divided into two groups according to the numerical random table method and named as the experimental group (n=50) and the control group (n=50). The control group received amiodarone alone, and the experimental group received amiodarone in combination with betaloc. The incidence of complications, blood pressure, heart rate changes, quality of life, and treatment effects were compared between the two groups. Results There was no significant difference in the quality of life score between the two groups before treatment(P>0.05). After treatment, the quality of life score of the experimental group was higher than that of the control group. There was statistically significant difference between the two groups (P<0.05). The total effective rate of the treatment group was 49 cases(98.00%) was higher than the control group 40 cases(80.00%)(χ^2=8.273 7,P=0.004 0). There was a statistically significant difference in the data comparison(P<0.05). There was no comparison between the two groups of patients before treatment, such as diastolic blood pressure, systolic blood pressure and heart rate. The statistically significant difference was(P>0.05). After treatment, the diastolic blood pressure and systolic blood pressure of the experimental group were lower than those of the control group. The heart rate was lower than that of the control group. There was statistically statistical significance between the two groups (P<0.05). The total incidence of complications in the experimental group was 2 cases(4.00%) was lower than the control group 11 cases(22.00%), and there was a statistically significant difference between the groups (P<0.05). Conclusion The combination of amiodarone and betaloc in the treatment of acute ventricular arrhythmia has a clinical effect, which can comprehensively stabilize the clinical indicators of patients, reduce the incidence of complications, and have higher clinical safety.