双胎妊娠孕期规范化诊疗和管理对围产儿预后的影响

Effect of Standardized Diagnosis and Treatment During Pregnancy on the Prognosis of Perinatal Infants

目的研究双胎妊娠孕期规范化诊疗和管理对围产儿预后的影响,为临床提供指导。方法选择从2015年8月—2018年8月收治的60例双胎妊娠孕妇纳入此次研究工作,按照数字随机分方式将其划分成两组,命名为实验组与对照组,各有30例。对照组接受常规诊疗和管理,实验组接受规范化诊疗和管理,对比两组孕妇产前超声绒毛膜性诊断比例、超声征象绒毛膜性诊断比例、超声诊断绒毛膜性符合率、新生儿评分、新生儿预后情况。结果经比较,实验组产前接受超声绒毛膜性诊断27例(90.00%),对照组产前接受超声绒毛膜性诊断20例(66.67%)(χ^2=4.811 8,P=0.028 2),实验组高于对照组,临床比较差异有统计学意义(P<0.05)。两组超声征象绒毛膜性诊断比较(χ^2=7.688 0,P=0.021 4),差异有统计学意义(P<0.05)。两组新生儿评分比较(t=7.961 5,P=0.018 6),组间比较差异有统计学意义(P<0.05)。两组新生儿预后情况比较(t=9.300 0,P=0.025 5),临床对比差异有统计学意义(P<0.05)。实验组孕妇超声诊断绒毛膜性符合率为100.00%,对照组为63.33%(χ^2=1.379 3,P=0.240 2),呈现差异无统计学意义(P>0.05)。结论将规范化诊疗和管理应用于双胎妊娠产妇孕期管理中,能够使围产儿预后效果明显改善,值得临床推广与应用。

Objective To study the effect of standardized diagnosis and treatment during pregnancy on the prognosis of perinatal infants,and to provide guidance for clinical practice.Methods Sixty pregnant women with twin pregnancies admitted from August 2015 to August 2018 were enrolled in the study.They were divided into two groups according to the numerical randomization method,named as experimental group and control group,with 30 cases in each group.The control group received routine diagnosis and management,and the experimental group received standardized diagnosis and management.The prenatal ultrasound choriomembrane diagnosis ratio,ultrasound imaging choriomembrane diagnosis ratio,ultrasound diagnosis of chorionic compliance,neonatal 1min Apgar score,and neonatal prognosis were compared between the two groups.Results By comparison,27 cases(90.00%)of the experimental group received prenatal ultrasound diagnosis of chorionic ultrasound,which was higher than that of the control group 20 cases(66.67%)(χ^2=4.811 8,P=0.028 2).And the clinical difference was significant(P<0.05).The two groups were compared for the diagnosis of chorionic ultrasonography(χ^2=7.688 0,P=0.021 4),with statistical significance(P<0.05).Neonatal 1min Apgar score of the two groups were compared(t=7.961 5,P=0.018 6),and there was a significant difference between the two groups(P<0.05).The prognosis of neonates in the two groups was compared(t=9.300 0,P=0.025 5),and the clinical comparison was statistically different(P<0.05).The coincidence rate of ultrasound diagnosis of chorionic membrane in pregnant women in the experimental group was 100.00%,and that in the control group was 63.33%(χ^2=1.379 3,P=0.240 2).There was no difference between the two groups(P>0.05).Conclusion The application of standardized diagnosis and treatment in the management of maternal pregnancy during twin pregnancy can significantly improve the prognosis of perinatal children,which is worthy of clinical promotion and application.