对比异丙酚复合瑞芬太尼靶控静脉麻醉与传统静脉复合麻醉的临床效果

Comparison of Clinical Effects of Propofol Combined with Remifentanil Target-Controlled Intravenous Anesthesia and Conventional Intravenous Anesthesia

目的对需要进行手术的患者分别通过异丙酚与瑞芬太尼进行靶控静脉麻醉以及传统方式的静脉复合麻醉,对患者产生的术中情况、麻醉效果以及不良情况的发生率展开比较,从而对异丙酚与瑞芬太尼靶控静脉麻醉效果进行评价。方法对该院在2016年5月—2018年1月期间内收治的患者随机抽取出需要进行手术的80例患者为研究对象,根据患者麻醉方式的不同将小组进行划分,划分成观察组和对照组,两组均由40例患者所构成。观察组患者通过异丙酚与瑞芬太尼进行联合靶控静脉麻醉,对照组患者通过传统方式的静脉复合麻醉,两组患者通过不同的麻醉方法之后,对两组患者的得到的术中情况、麻醉效果以及不良情况的发生率展开比较,从而对异丙酚与瑞芬太尼进行联合靶控静脉麻醉的麻醉效果进行评价,以期为临床中麻醉方法提供有力的依据,从而对麻醉效果进行评价。结果观察组患者通过异丙酚复合瑞芬太尼进行靶控静脉麻醉后,术中心率(70.60±10.90)次/min,舒张压(58.16±12.06)mmHg,收缩压(113.60±20.50)mmHg,平均动脉压(75.29±10.28)mmHg,对照组患者通过传统方式的静脉复合麻醉后,术中心率(60.60±11.20)次/min,舒张压(45.17±11.25)mmHg,收缩压(90.60±18.50)mmHg,平均动脉压(60.21±11.28)mmHg,差异有统计学意义(t=6.254 8,5.943 8,6.165 8,5.348 2,P<0.05),说明异丙酚符合瑞芬太尼靶控静脉麻醉的麻醉有效性;观察组患者的定向力恢复时间:(12.60±3.95)d,VAS评分:(3.95±0.46)分,呼吸恢复时间:(11.96±3.98)d,清醒时间:(11.34±4.98)d,显著高于对照组(t=6.548 2、6.219 8、6.354 8、6.498 2,P<0.05);观察组患者的不良反应发生率为7.5%(3/40),对照组患者的不良反应发生率为25.0%(10/40)。结论需要手术的患者通过异丙酚符合瑞芬太尼靶控静脉麻醉,患者的麻醉效果更加优良,安全性更高,值得在临床中推广以及应用。

Objective Target-controlled intravenous anesthesia with propofol and remifentanil and conventional intravenous anesthesia were performed on patients requiring surgery,respectively.The incidence of intraoperative,anesthetic,and adverse events was compared between the patients,in order to get the evaluation of propofol and remifentanil target-controlled intravenous anesthesia Methods From May 2016 to January 2018,80 patients who needed surgery and were admitted to our hospital during this period were randomly selected.They were considered as the research targets of the sub-study according to the patient's anesthesia method.They were divided into observation group and control group,with 40 patients in each group.Patients in the observation group underwent combined target-controlled intravenous anesthesia with propofol and remifentanil,and patients in the control group underwent conventional intravenous anesthesia.After receiving different anesthesia methods,the intraoperative status,anesthetic effect and the incidence of adverse conditions of the two groups were compared to evaluate the anesthetic effect of propofol and remifentanil in combination with target-controlled intravenous anesthesia,in order to provide a strong basis for the evaluation of clinical anesthesia methods.Results In the observation group,the target center rate was(70.60±10.9)times/min,diastolic blood pressure was(58.16±12.06)mmHg,systolic blood pressure was(113.6±20.5)mmHg,and mean arterial pressure was(75.29±10.28)mmHg after propofol combined with remifentanil for target-controlled intravenous anesthesia.And in the control group,after undergoing traditional combined intravenous anesthesia,the central rate was(60.6±11.2)times/min,diastolic blood pressure was(45.17±11.25)mmHg,systolic blood pressure was(90.60±18.5)mmHg,and mean arterial pressure was(60.21±11.28)mmHg.The difference between the two groups was statistically significant(t=6.254 8,5.943 8,6.165 8,5.348 2,P<0.05),indicating that propofol meets the anesthetic effectiveness of remifentanil target-controlled intravenous anesthesia.The recovery time of the directed force in the observation group was(12.60±3.95)d,VAS score was(3.95±0.46)points,respiratory recovery time was(11.96±3.98)d,waking time was(11.34±4.98)d,which were significantly higher than those in the control group(t=6.548 2,6.219 8,6.354 8,6.498 2,P<0.05).The incidence of adverse reactions was 7.5%(3/40)in the observation group,and was 25.0%(10/40)in the control group.Conclusion The anesthetic effect of propofol in accordance with remifentanil target-controlled intravenous anesthesia is excellent and safe in the treatment of the patients requiring surgery.And it is worthy of promotion and application in the clinic.